High-level humidity can increase drug degradation rates. That's why pharmaceutical products are always packed with precise packaging of air.
The humidity level greatly influences the stability of the pills. Tablets and capsules are protected for moisture through their packing. When the number of tablets and capsules are low, they get high humidity and this is also reflected in their actual form. There are different ways of affecting tablet stability as discussed in this article.
1. Decrease in hardness
Various humidity conditions that have been affected by changes in the rigidity of the tablet lasting longer than six months have been investigated. All samples used show a 75% relative humidity and 5 to 10% 25 degrees and 45 degrees at 10-3 9% hardness. There is no difference between reducing hardness on 100% relative humidity. High-humidity pills absorb moisture, which can adversely affect its rigidity.
2. Results on stability
Physical stability of medicines is one thing that should be considered because it can affect the effectiveness of a drug. To make the drug effective, it is necessary to maintain certain viscosity such as physical stability. When the humidity is absorbed in the tablet it affects body stability that makes the tablet ineffective. This product can now be considered a deformity product. Many people feel that these brooding products are inactive and are not harmful, which are not true. In fact, cancer is one of the adverse effects of these products.
3. Impact on Tablet Properties
The easiest and easiest way to manage drugs in the body is to use tablets. Due to the physico-chemical properties of the drug, it has a great effect on the dissociative rate such as dissolving rate and the content of the drug. The widely used technology used for tablet production is wet granulation. The advantages have crossed the wet granulation in direct compression, so they can be used extensively.
4. Effects of granularity
Two tablets were used to check the humidity of the pencils in order to effectively monitor the granularity of the pills. One of the tablets was kept in frozen conditions, while the other was placed in a high humidity position. Then both the tablet X-ray Micro CT images were taken differently. The X-ray microscopic CT image was acquired by the non-blocking tablets at different humidity levels. The tablets placed in sterile conditions have found some cracks inside the interior. More extensive interconnected cracks are found in high-humidity tablets. Micro differences can also be seen in indoor look granularity.
5. Degradation
Receiving the main quality objective stability of the drug tablet. The main purpose of the experiments to reduce the thermal stress for the development of products in the objective targeted objectives for the purpose of the solution and liquid product drug substances.
Therefore, it should be a role of interaction with humidity and thermal stress, that it can be easy to approximate the residues of solids, such as pills. Humidity conditions can cause unexpected changes in the physical condition of the tablet, such as hydrating / dehydration or chicks, and therefore combined storage relative humidity with temperature. The future of technology can be fulfilled successfully. It has been received for any humidity value.
